Helping The others Realize The Advantages Of pkrrating
The interfacial residues are highly conserved among eIF2α kinases and mutagenesis implicates the BTB dimer in PKR function18. FRET measurements show which the kinase domains dimerize when PKR binds to activating dsRNAs19. These observations help a product exactly where activating RNA serves as a scaffold to bind several PKR monomers, escalating th